Suppositories Notes Download for B.pharm and D.Pharm students.
Suppositories are solid dosage forms intended for insertion into body orifices where they melt, soften, or dissolve and exert localized or systemic effects.
ADVANTAGES:
_ Can exert local effect on rectal mucosa.
_ Used to promote evacuation of bowel.
_ Avoid any gastrointestinal irritation.
_ Can be used in unconscious patients (e.g. during
fitting).
_ Can be used for systemic absorption of drugs and
avoid first-pass metabolism.
− Babies or old people who cannot swallow oral
medication.
− Post operative people who cannot be administered
oral medication.
− People suffering from severe nausea or vomiting.