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Non-aqueous Titrations PDF Notes Free Download For Pharmacy Students.
Non Aqueous Titrations
Most of the titrations are performed in the aqueous media, means water is used as solvent.
There may be difficulty if reactant is insoluble in water or reactant is reactive with water or the analyte (sample) is either too weak acid or too weak base.
Those too weak acids or bases can’t be titrated in aqueous solution due to the amphoteric behavior of water (i.e water can react as an acid on titration with a base and act as a base on titration with acid). So water will compete with the sample if it is weak acid or weak base.
The simple solution for this problem is to replace water as solvent with another non aqueous solvent, so this type of titration is named “Non Aqueous Titrations”.
Reasons for Non aqueous titrations:
The reactant is insoluble in water.
The reactant is reactive with water.
The sample is too weak acid or too weak base.